Agilent Technology acquires MassCode Tag technology from Eurofins MWG Operon Agilent Technology Inc.

In MassTag PCR, individual tags are attached to DNA primers that match microbial sequences. The primers are after that utilized to amplify nucleic acid isolated from biological sample using PCR. The tags are released through the use of UV irradiation, and mass spectroscopy can be used to recognize the corresponding tags then. The mass spectroscopy recognition technique is highly multiplexed, faster and more sensitive than traditional detection technologies utilized for PCR evaluation. Investigators at the Center for Immunity and Contamination in the Mailman College of Public Health, Columbia University, developed the MassTag PCR program.D., John Snow professor of Epidemiology at Columbia University. Dr. Lipkin, along with Dr. Thomas Briese, associate professor of Epidemiology at Columbia, have utilized this technology within their research to help expand innovative techniques of pathogen identification and discovery for unexplained respiratory infections, viral hemorrhagic fevers, and meningoencephalitis.The study comprises 374 postmenopausal ladies who developed breast tumor and 374 healthy females as controls. All earlier epidemiological studies have been based on food frequency questionnaires. The researchers behind this study have instead used biological markers in order to even more accurately determine the acrylamide levels ingested by the women participating in the analysis. The findings show a positive association between an elevated acrylamide-haemoglobin level and the development of breast tumor after adjustment for smoking behaviour. The risk of breast cancer doubles with a upsurge in the acrylamide-haemoglobin level tenfold. A tenfold increase in the acrylamide-haemoglobin level corresponds more or less to the difference measured between the women with the cheapest and highest exposure.