But also for some patients the drug isnt effective.

The reason for this level of resistance was unclear until this week when researchers from Virginia Commonwealth University Massey Cancer Middle demonstrated that a protein referred to as AEG-1 blocks the effects of retinoic acid in leukemia and liver malignancy. Because AEG-1 is certainly overexpressed in just about any cancer, these findings could impact the care of countless cancer sufferers. Details of the scholarly study were published this week in the web edition of the journal Tumor Research, a journal of the American Association for Cancer Research. The team of scientists led by Devanand Sarkar, M.B.B.S., Ph.D., demonstrated that the proteins AEG-1 binds to retinoid X receptors , which help regulate cell development and growth.Sue Duval, an associate professor of biostatistics and cardiology, led the project. The study was published online Sept. 28 in the Journal of the American University of Cardiology. The findings highlight the necessity to get PAD patients to avoid smoking, which can benefit their health and significantly reduce their medical costs, Dr. Elizabeth Jackson, of the University of Michigan Wellness System, wrote within an accompanying editorial.

Alcohol may promote scarring and airway damage after transplantation A recent study using an animal model of lung transplants shows that chronic alcohol usage by the donor promotes scarring and airway injury after transplantation.