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Dalantercept is a novel protein therapeutic that targets the activin receptor-like kinase 1 pathway and inhibits angiogenesis through a system specific from that of anti-angiogenic therapies currently used to treat various cancers. The phase 2, open-label research is normally chaired by Robert Burger, M.D., Director of the Women's Cancer Center and Professor in the Section of Surgical Oncology at the Fox Chase Tumor Center in Philadelphia, Pa. Acceleron, its companions, and collaborators have finally initiated seven phase 2 studies across three of Acceleron's programs – dalantercept , sotatercept , and ACE-536 – since November of 2012.